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Atypical antidepressants extend lifespan of Caenorhabditis elegans by activation of a non‐cell‐autonomous stress response

Oxidative stress has long been associated with aging and has recently been linked to psychiatric disorders, including psychosis and depression. We identified multiple antipsychotics and antidepressants that extend Caenorhabditis elegans lifespan and protect the animal from oxidative stress. Here, we...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Rangaraju, Sunitha, Solis, Gregory M., Andersson, Sofia I., Gomez‐Amaro, Rafael L., Kardakaris, Rozina, Broaddus, Caroline D., Niculescu, Alexander B., Petrascheck, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693466/
https://ncbi.nlm.nih.gov/pubmed/26255886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12379
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