Suppression of transcriptional drift extends C. elegans lifespan by postponing the onset of mortality

Longevity mechanisms increase lifespan by counteracting the effects of aging. However, whether longevity mechanisms counteract the effects of aging continually throughout life, or whether they act during specific periods of life, preventing changes that precede mortality is unclear. Here, we uncover...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Rangaraju, Sunitha, Solis, Gregory M, Thompson, Ryan C, Gomez-Amaro, Rafael L, Kurian, Leo, Encalada, Sandra E, Niculescu, Alexander B, Salomon, Daniel R, Petrascheck, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2015
Konular:
Computational and Systems Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720515/
https://ncbi.nlm.nih.gov/pubmed/26623667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08833
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