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G(s)α deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight
G(s)α, the G protein that transduces receptor-stimulated cAMP generation, mediates sympathetic nervous system stimulation of brown adipose tissue (BAT) thermogenesis and browning of white adipose tissue (WAT), which are both potential targets for treating obesity, as well as lipolysis. We generated...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4720348/ https://ncbi.nlm.nih.gov/pubmed/26712027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517142113 |
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