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G(s)α deficiency in adipose tissue improves glucose metabolism and insulin sensitivity without an effect on body weight

G(s)α, the G protein that transduces receptor-stimulated cAMP generation, mediates sympathetic nervous system stimulation of brown adipose tissue (BAT) thermogenesis and browning of white adipose tissue (WAT), which are both potential targets for treating obesity, as well as lipolysis. We generated...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Li, Yong-Qi, Shrestha, Yogendra B., Chen, Min, Chanturiya, Tatyana, Gavrilova, Oksana, Weinstein, Lee S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720348/
https://ncbi.nlm.nih.gov/pubmed/26712027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1517142113
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