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Increased glucose tolerance and reduced adiposity in the absence of fasting hypoglycemia in mice with liver-specific G(s)α deficiency
The G protein G(s)α is essential for hormone-stimulated cAMP generation and is an important metabolic regulator. We investigated the role of liver G(s)-signaling pathways by developing mice with liver-specific G(s)α deficiency (LGsKO mice). LGsKO mice had increased liver weight and glycogen content...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1257533/ https://ncbi.nlm.nih.gov/pubmed/16239968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI24196 |
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