BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells

Naive mouse embryonic stem cells (mESCs) are in a metastable state and fluctuate between inner cell mass- and epiblast-like phenotypes. Here, we show transient activation of the BMP-SMAD signaling pathway in mESCs containing a BMP-SMAD responsive reporter transgene. Activation of the BMP-SMAD report...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Stem Cell Reports
मुख्य लेखकों: Gomes Fernandes, Maria, Dries, Ruben, Roost, Matthias S., Semrau, Stefan, de Melo Bernardo, Ana, Davis, Richard P., Ramakrishnan, Ramprasad, Szuhai, Karoly, Maas, Elke, Umans, Lieve, Abon Escalona, Vanesa, Salvatori, Daniela, Deforce, Dieter, Van Criekinge, Wim, Huylebroeck, Danny, Mummery, Christine, Zwijsen, An, Chuva de Sousa Lopes, Susana M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Elsevier 2015
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4720007/
https://ncbi.nlm.nih.gov/pubmed/26711875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.11.012
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