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Absence of TDP‐43 is difficult to digest
It is well established that TDP‐43 accumulates in degenerating neurons in patients with ALS/FTLD, which might affect normal TDP‐43 function. In this issue of The EMBO Journal Xia et al (2016) show a novel connection between TDP‐43 loss of function and autophagy failure. Using knockdown models of TDP...
Guardat en:
| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley and Sons Inc.
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4718458/ https://ncbi.nlm.nih.gov/pubmed/26702101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201593603 |
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