Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK

BACKGROUND: Activation of NADPH oxidase (PHOX) plays a critical role in mediating dopaminergic neuroinflammation. In the present study, we investigated the role of PHOX in methamphetamine (MA)-induced neurotoxic and inflammatory changes in mice. METHODS: We examined changes in mitogen-activated prot...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Neuroinflammation
Hoofdauteurs: Dang, Duy-Khanh, Shin, Eun-Joo, Nam, Yunsung, Ryoo, Sungwoo, Jeong, Ji Hoon, Jang, Choon-Gon, Nabeshima, Toshitaka, Hong, Jau-Shyong, Kim, Hyoung-Chun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717833/
https://ncbi.nlm.nih.gov/pubmed/26780950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0478-x
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items