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Ethers and esters derived from apocynin avoid the interaction between p47phox and p22phox subunits of NADPH oxidase: evaluation in vitro and in silico
NOX (NADPH oxidase) plays an important role during several pathologies because it produces the superoxide anion (O(2)(•−)), which reacts with NO (nitric oxide), diminishing its vasodilator effect. Although different isoforms of NOX are expressed in ECs (endothelial cells) of blood vessels, the NOX2...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Portland Press Ltd.
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3731894/ https://ncbi.nlm.nih.gov/pubmed/23802190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20130029 |
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