Ethers and esters derived from apocynin avoid the interaction between p47phox and p22phox subunits of NADPH oxidase: evaluation in vitro and in silico

NOX (NADPH oxidase) plays an important role during several pathologies because it produces the superoxide anion (O(2)(•−)), which reacts with NO (nitric oxide), diminishing its vasodilator effect. Although different isoforms of NOX are expressed in ECs (endothelial cells) of blood vessels, the NOX2...

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Detalles Bibliográficos
Autores principales: Macías-Pérez, Martha Edith, Martínez-Ramos, Federico, Padilla-Martínez, Itzia Irene, Correa-Basurto, José, Kispert, Lowell, Mendieta-Wejebe, Jessica Elena, Rosales-Hernández, Martha Cecilia
Formato: Artigo
Lenguaje:Inglês
Publicado: Portland Press Ltd. 2013
Materias:
Original Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731894/
https://ncbi.nlm.nih.gov/pubmed/23802190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20130029
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