טוען...
Multi-omic measurement of mutually exclusive loss-of-function enriches for candidate synthetic lethal gene pairs
BACKGROUND: Identification of synthetic lethal interactions in cancer cells could offer promising new therapeutic targets. Large-scale functional genomic screening presents an opportunity to test large numbers of cancer synthetic lethal hypotheses. Methods enriching for candidate synthetic lethal ta...
שמור ב:
| הוצא לאור ב: | BMC Genomics |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4717622/ https://ncbi.nlm.nih.gov/pubmed/26781748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2375-1 |
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