Caricamento...
Multi-omic measurement of mutually exclusive loss-of-function enriches for candidate synthetic lethal gene pairs
BACKGROUND: Identification of synthetic lethal interactions in cancer cells could offer promising new therapeutic targets. Large-scale functional genomic screening presents an opportunity to test large numbers of cancer synthetic lethal hypotheses. Methods enriching for candidate synthetic lethal ta...
Salvato in:
| Pubblicato in: | BMC Genomics |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4717622/ https://ncbi.nlm.nih.gov/pubmed/26781748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2375-1 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|