Protection against acetaminophen-induced acute liver failure by omentum adipose tissue derived stem cells through the mediation of Nrf2 and cytochrome P450 expression

BACKGROUND: Acetaminophen (APAP) overdose causes acute liver failure (ALF) in animals and humans via the rapid depletion of intracellular glutathione (GSH) and the generation of excess reactive oxygen species (ROS) that damage hepatocytes. Stem cell therapy is a potential treatment strategy for ALF....

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biomed Sci
Prif Awduron: Huang, Yu-Jen, Chen, Poda, Lee, Chih-Yuan, Yang, Sin-Yu, Lin, Ming-Tsan, Lee, Hsuan-Shu, Wu, Yao-Ming
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717531/
https://ncbi.nlm.nih.gov/pubmed/26787241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-016-0231-x
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