Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD‐deficient IGFBP‐2 variant in female transgenic mice

Impaired growth is often associated with an extension of lifespan. However, the negative correlation between somatic growth and life expectancy is only true within, but not between, species. This can be observed because smaller species have, as a rule, a shorter lifespan than larger species. In inse...

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Publié dans:Aging Cell
Auteurs principaux: Hoeflich, Andreas, Reyer, Anja, Ohde, Daniela, Schindler, Nancy, Brenmoehl, Julia, Spitschak, Marion, Langhammer, Martina, Tuchscherer, Armin, Wirthgen, Elisa, Renner‐Müller, Ingrid, Wanke, Rüdiger, Metzger, Friedrich, Bielohuby, Maximilian, Wolf, Eckhard
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2015
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4717279/
https://ncbi.nlm.nih.gov/pubmed/26507795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12413
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