Overlap of Peak Growth Activity and Peak IGF-1 to IGFBP Ratio: Delayed Increase of IGFBPs Versus IGF-1 in Serum as a Mechanism to Speed up and down Postnatal Weight Gain in Mice

Forced expression of insulin-like growth factor binding proteins (IGFBPs) in transgenic mice has clearly revealed inhibitory effects on somatic growth. However, by this approach, it cannot be solved if or how IGFBPs rule insulin-like growth factor (IGF)-dependent growth under normal conditions. In o...

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Publicado en:Cells
Main Authors: Walz, Michael, Chau, Luong, Walz, Christina, Sawitzky, Mandy, Ohde, Daniela, Brenmoehl, Julia, Tuchscherer, Armin, Langhammer, Martina, Metzger, Friedrich, Höflich, Christine, Hoeflich, Andreas
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7348928/
https://ncbi.nlm.nih.gov/pubmed/32580353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9061516
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