Reduced Fragmentation of IGFBP-2 and IGFBP-3 as a Potential Mechanism for Decreased Ratio of IGF-II to IGFBPs in Cerebrospinal Fluid in Response to Repeated Intrathecal Administration of Triamcinolone Acetonide in Patients With Multiple Sclerosis

Multiple sclerosis (MS) is a chronic autoimmune disease of the brain and spinal cord causing a wide range of symptoms such as impaired walking capability, spasticity, fatigue, and pain. The insulin-like growth factor (IGF) system has regulatory functions for the induction of inflammatory pathways in...

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Detalles Bibliográficos
Publicado en:Front Endocrinol (Lausanne)
Autores principales: Hoeflich, Andreas, Fitzner, Brit, Walz, Christina, Hecker, Michael, Tuchscherer, Armin, Brenmoehl, Julia, Zettl, Uwe Klaus
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Endocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7813808/
https://ncbi.nlm.nih.gov/pubmed/33469444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2020.565557
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