Endotoxin-Induced Tryptophan Degradation along the Kynurenine Pathway: The Role of Indolamine 2,3-Dioxygenase and Aryl Hydrocarbon Receptor-Mediated Immunosuppressive Effects in En...

por Wirthgen, Elisa, Hoeflich, Andreas
Publicado no J Amino Acids (2015)

Limitations and Off-Target Effects of Tryptophan-Related IDO Inhibitors in Cancer Treatment

por Günther, Juliane, Däbritz, Jan, Wirthgen, Elisa
Publicado no Front Immunol (2019)

Biomarkers Predictive of Response to Thiopurine Therapy in Inflammatory Bowel Disease

por Cornish, Jack S., Wirthgen, Elisa, Däbritz, Jan
Publicado no Front Med (Lausanne) (2020)

Kynurenic Acid: The Janus-Faced Role of an Immunomodulatory Tryptophan Metabolite and Its Link to Pathological Conditions

por Wirthgen, Elisa, Hoeflich, Andreas, Rebl, Alexander, Günther, Juliane
Publicado no Front Immunol (2018)

Editorial: Immunomodulatory Roles of Tryptophan Metabolites in Inflammation and Cancer

por Günther, Juliane, Fallarino, Francesca, Fuchs, Dietmar, Wirthgen, Elisa
Publicado no Front Immunol (2020)

The Immunomodulator 1-Methyltryptophan Drives Tryptophan Catabolism Toward the Kynurenic Acid Branch

por Wirthgen, Elisa, Leonard, Anne K., Scharf, Christian, Domanska, Grazyna
Publicado no Front Immunol (2020)

Control of IGFBP-2 Expression by Steroids and Peptide Hormones in Vertebrates

por Hoeflich, Andreas, Wirthgen, Elisa, David, Robert, Classen, Carl Friedrich, Spitschak, Marion, Brenmoehl, Julia
Publicado em 2014

Circulating insulin-like growth factor-related biomarkers: Correlates and responses to calcium supplementation in colorectal adenoma patients

por Um, Caroline Y., Fedirko, Veronika, Flanders, W. Dana, Höflich, Christine, Wirthgen, Elisa, Bostick, Roberd M.
Publicado no Mol Carcinog (2017)

Pharmacokinetics of 1-methyl-L-tryptophan after single and repeated subcutaneous application in a porcine model

por Wirthgen, Elisa, Kanitz, Ellen, Tuchscherer, Margret, Tuchscherer, Armin, Domanska, Grazyna, Weitschies, Werner, Seidlitz, Anne, Scheuch, Eberhard, Otten, Winfried
Publicado no Exp Anim (2015)

Partial phenotype conversion and differential trait response to conditions of husbandry in mice

por Brenmoehl, Julia, Walz, Christina, Spitschak, Marion, Wirthgen, Elisa, Walz, Michael, Langhammer, Martina, Tuchscherer, Armin, Naumann, Ronald, Hoeflich, Andreas
Publicado no J Comp Physiol B (2017)

Effects of Transport Duration and Environmental Conditions in Winter or Summer on the Concentrations of Insulin-Like Growth Factors and Insulin-Like Growth Factor-Binding Proteins...

por Wirthgen, Elisa, Goumon, Sébastien, Kunze, Martin, Walz, Christina, Spitschak, Marion, Tuchscherer, Armin, Brown, Jennifer, Höflich, Christine, Faucitano, Luigi, Hoeflich, Andreas
Publicado no Front Endocrinol (Lausanne) (2018)

Increased Concentrations of Insulin-Like Growth Factor Binding Protein (IGFBP)-2, IGFBP-3, and IGFBP-4 Are Associated With Fetal Mortality in Pregnant Cows

por Mense, Kirsten, Heidekorn-Dettmer, Julia, Wirthgen, Elisa, Brockelmann, Yette, Bortfeldt, Ralf, Peter, Sarah, Jung, Markus, Höflich, Christine, Hoeflich, Andreas, Schmicke, Marion
Publicado no Front Endocrinol (Lausanne) (2018)

Effects of Feeding Milk Replacer Ad Libitum or in Restricted Amounts for the First Five Weeks of Life on the Growth, Metabolic Adaptation, and Immune Status of Newborn Calves

por Schäff, Christine T., Gruse, Jeannine, Maciej, Josefine, Mielenz, Manfred, Wirthgen, Elisa, Hoeflich, Andreas, Schmicke, Marion, Pfuhl, Ralf, Jawor, Paulina, Stefaniak, Tadeusz, Hammon, Harald M.
Publicado no PLoS One (2016)

Effects of 1-Methyltryptophan on Immune Responses and the Kynurenine Pathway after Lipopolysaccharide Challenge in Pigs

por Wirthgen, Elisa, Otten, Winfried, Tuchscherer, Margret, Tuchscherer, Armin, Domanska, Grazyna, Brenmoehl, Julia, Günther, Juliane, Ohde, Daniela, Weitschies, Werner, Seidlitz, Anne, Scheuch, Eberhard, Kanitz, Ellen
Publicado no Int J Mol Sci (2018)

Activation of the Kynurenine Pathway in Human Malignancies Can Be Suppressed by the Cyclin-Dependent Kinase Inhibitor Dinaciclib

por Riess, Christin, Schneider, Björn, Kehnscherper, Hanna, Gesche, Julia, Irmscher, Nina, Shokraie, Fatemeh, Classen, Carl Friedrich, Wirthgen, Elisa, Domanska, Grazyna, Zimpfer, Annette, Strüder, Daniel, Junghanss, Christian, Maletzki, Claudia
Publicado no Front Immunol (2020)

Dissociation of somatic growth, time of sexual maturity, and life expectancy by overexpression of an RGD‐deficient IGFBP‐2 variant in female transgenic mice

por Hoeflich, Andreas, Reyer, Anja, Ohde, Daniela, Schindler, Nancy, Brenmoehl, Julia, Spitschak, Marion, Langhammer, Martina, Tuchscherer, Armin, Wirthgen, Elisa, Renner‐Müller, Ingrid, Wanke, Rüdiger, Metzger, Friedrich, Bielohuby, Maximilian, Wolf, Eckhard
Publicado no Aging Cell (2015)

Validation of serum IGF-I as a biomarker to monitor the bioactivity of exogenous growth hormone agonists and antagonists in rabbits

por Bielohuby, Maximilian, Zarkesh-Esfahani, Sayyed Hamid, Manolopoulou, Jenny, Wirthgen, Elisa, Walpurgis, Katja, Toghiany Khorasgani, Mohaddeseh, Aghili, Zahra Sadat, Wilkinson, Ian Robert, Hoeflich, Andreas, Thevis, Mario, Ross, Richard J., Bidlingmaier, Martin
Publicado em 2014

Serum IGFBP4 concentration decreased in dairy heifers towards day 18 of pregnancy

por Meyerholz, Marie M, Mense, Kirsten, Lietzau, Michael, Kassens, Ana, Linden, Matthias, Knaack, Hendrike, Wirthgen, Elisa, Hoeflich, Andreas, Raliou, Mariam, Richard, Christophe, Sandra, Olivier, Schuberth, Hans-Joachim, Hoedemaker, Martina, Schmicke, Marion
Publicado no J Vet Sci (2015)

Interference of stress with the somatotropic axis in pigs – lights on new biomarkers

por Wirthgen, Elisa, Kunze, Martin, Goumon, Sébastien, Walz, Christina, Höflich, Christine, Spitschak, Marion, Brenmoehl, Julia, Kanitz, Ellen, Tuchscherer, Margret, Otten, Winfried, Gimsa, Ulrike, Schön, Peter, Manteuffel, Christian, Tuchscherer, Armin, Pfuhl, Ralf, Metges, Cornelia C., Stabenow, Bernd, Erdmann, Sandra, Schluricke, Kathleen, Faucitano, Luigi, Hoeflich, Andreas
Publicado no Sci Rep (2017)

Immunomodulatory Roles of Tryptophan Metabolites in Inflammation and Cancer

Publicado em 2020