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Production of the polyketide 6-deoxyerythronolide B in the heterologous host Bacillus subtilis
Polyketides, such as erythromycin, are complex natural products with diverse therapeutic applications. They are synthesized by multi-modular megaenzymes, so-called polyketide synthases (PKSs). The macrolide core of erythromycin, 6-deoxyerythronolide B (6dEB), is produced by the deoxyerythronolide B...
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| Publicado no: | Appl Microbiol Biotechnol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4717160/ https://ncbi.nlm.nih.gov/pubmed/26432460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00253-015-6990-6 |
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