Biosynthesis of Yersiniabactin, a Complex Polyketide-Nonribosomal Peptide, Using Escherichia coli as a Heterologous Host

The medicinal value associated with complex polyketide and nonribosomal peptide natural products has prompted biosynthetic schemes dependent upon heterologous microbial hosts. Here we report the successful biosynthesis of yersiniabactin (Ybt), a model polyketide-nonribosomal peptide hybrid natural p...

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Bibliografiske detaljer

Udgivet i:	Appl Environ Microbiol
Principais autores:	Pfeifer, Blaine A., Wang, Clay C. C., Walsh, Christopher T., Khosla, Chaitan
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2003
Fag:	Physiology and Biotechnology
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14602630/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.11.6698-6702.2003
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