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Biosynthesis of Yersiniabactin, a Complex Polyketide-Nonribosomal Peptide, Using Escherichia coli as a Heterologous Host

The medicinal value associated with complex polyketide and nonribosomal peptide natural products has prompted biosynthetic schemes dependent upon heterologous microbial hosts. Here we report the successful biosynthesis of yersiniabactin (Ybt), a model polyketide-nonribosomal peptide hybrid natural p...

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Detaylı Bibliyografya
Asıl Yazarlar: Pfeifer, Blaine A., Wang, Clay C. C., Walsh, Christopher T., Khosla, Chaitan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2003
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC262314/
https://ncbi.nlm.nih.gov/pubmed/14602630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.11.6698-6702.2003
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