Biosynthesis of Yersiniabactin, a Complex Polyketide-Nonribosomal Peptide, Using Escherichia coli as a Heterologous Host

The medicinal value associated with complex polyketide and nonribosomal peptide natural products has prompted biosynthetic schemes dependent upon heterologous microbial hosts. Here we report the successful biosynthesis of yersiniabactin (Ybt), a model polyketide-nonribosomal peptide hybrid natural p...

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Bibliografski detalji

Izdano u:	Appl Environ Microbiol
Glavni autori:	Pfeifer, Blaine A., Wang, Clay C. C., Walsh, Christopher T., Khosla, Chaitan
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2003
Teme:	Physiology and Biotechnology
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC262314/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14602630/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.11.6698-6702.2003
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