Germline BAP1 mutational landscape of asbestos-exposed malignant mesothelioma patients with family history of cancer

Heritable mutations in the BAP1 tumor suppressor gene predispose individuals to mesothelioma and other cancers. However, a large-scale assessment of germline BAP1 mutation incidence and associated clinical features in mesothelioma patients with a family history of cancer has not been reported. There...

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Udgivet i:Cancer Res
Main Authors: Ohar, Jill A., Cheung, Mitchell, Talarchek, Jacqueline, Howard, Suzanne E., Howard, Timothy D., Hesdorffer, Mary, Peng, Hongzhuang, Rauscher, Frank J., Testa, Joseph R.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715907/
https://ncbi.nlm.nih.gov/pubmed/26719535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0295
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