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An asbestos-exposed family with multiple cases of pleural malignant mesothelioma without inheritance of a predisposing BAP1 mutation

We report a family with domestic exposure to asbestos and multiple cancers, including eight pleural malignant mesotheliomas and several other lung/pleural tumors. DNA sequence analysis revealed no evidence for an inherited mutation of BAP1. Sequence analysis of other potentially relevant genes, incl...

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Detalhes bibliográficos
Publicado no:Cancer Genet
Main Authors: Cheung, Mitchell, Kadariya, Yuwaraj, Pei, Jianming, Talarchek, Jacqueline, Facciolo, Francesco, Visca, Paolo, Righi, Luisella, Cozzi, Ilaria, Testa, Joseph R., Ascoli, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608746/
https://ncbi.nlm.nih.gov/pubmed/26364129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2015.07.004
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