Dominant negative Ras attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy

The importance of the oncogene Ras in cardiac hypertrophy is well appreciated. The hypertrophic effects of the constitutively active mutant Ras-Val12 are revealed by clinical syndromes due to the Ras mutations and experimental studies. We examined the possible anti-hypertrophic effect of Ras inhibit...

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Vydáno v:Biochim Biophys Acta
Hlavní autoři: Ramos-Kuri, Manuel, Rapti, Kleopatra, Mehel, Hind, Zhang, Shihong, Dhandapany, Perundurai S., Liang, Lifan, García-Carrancá, Alejandro, Bobe, Regis, Fischmeister, Rodolphe, Adnot, Serge, Lebeche, Djamel, Hajjar, Roger J., Lipskaia, Larissa, Chemaly, Elie R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715892/
https://ncbi.nlm.nih.gov/pubmed/26260012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2015.08.006
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