Differential patterns of replacement and reactive fibrosis in pressure and volume overload are related to the propensity for ischaemia and involve resistin

Pathological left ventricle (LV) hypertrophy (LVH) results in reactive and replacement fibrosis. Volume overload LVH (VOH) is less profibrotic than pressure overload LVH (POH). Studies attribute subendocardial fibrosis in POH to ischaemia, and reduced fibrosis in VOH to collagen degradation favourin...

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Detalhes bibliográficos
Main Authors: Chemaly, Elie R, Kang, Soojeong, Zhang, Shihong, McCollum, LaTronya, Chen, Jiqiu, Bénard, Ludovic, Purushothaman, K-Raman, Hajjar, Roger J, Lebeche, Djamel
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3936371/
https://ncbi.nlm.nih.gov/pubmed/24018949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.258731
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