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Resistin Promotes Cardiac Hypertrophy via the AMP-activated Protein Kinase/Mammalian Target of Rapamycin (AMPK/mTOR) and c-Jun N-terminal Kinase/Insulin Receptor Substrate 1 (JNK/IRS1) Pathways

Resistin has been suggested to be involved in the development of diabetes and insulin resistance. We recently reported that resistin is expressed in diabetic hearts and promotes cardiac hypertrophy; however, the mechanisms underlying this process are currently unknown. Therefore, we wanted to elucid...

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Detalhes bibliográficos
Main Authors: Kang, Soojeong, Chemaly, Elie R., Hajjar, Roger J., Lebeche, Djamel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099663/
https://ncbi.nlm.nih.gov/pubmed/21478152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.200022
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