Generation of GFAP::GFP astrocyte reporter lines from human adult fibroblast-derived iPS cells using zinc-finger nuclease technology

Astrocytes are instrumental to major brain functions, including metabolic support, extracellular ion regulation, the shaping of excitatory signaling events and maintenance of synaptic glutamate homeostasis. Astrocyte dysfunction contributes to numerous developmental, psychiatric and neurodegenerativ...

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Vydáno v:Glia
Hlavní autoři: Zhang, Ping-Wu, Haidet-Phillips, Amanda M., Pham, Jacqueline T., Lee, Youngjin, Huo, Yuqing, Tienari, Pentti J., Maragakis, Nicholas J., Sattler, Rita, Rothstein, Jeffrey D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715664/
https://ncbi.nlm.nih.gov/pubmed/26295203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22903
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