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Zinc-finger nuclease-mediated correction of α-thalassemia in iPS cells
Induced pluripotent stem (iPS) cell technology holds vast promises for a cure to the hemoglobinopathies. Constructs and methods to safely insert therapeutic genes to correct the genetic defect need to be developed. Site-specific insertion is a very attractive method for gene therapy because the risk...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3543982/ https://ncbi.nlm.nih.gov/pubmed/23002118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-03-420703 |
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