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Generation of GFAP::GFP astrocyte reporter lines from human adult fibroblast-derived iPS cells using zinc-finger nuclease technology

Astrocytes are instrumental to major brain functions, including metabolic support, extracellular ion regulation, the shaping of excitatory signaling events and maintenance of synaptic glutamate homeostasis. Astrocyte dysfunction contributes to numerous developmental, psychiatric and neurodegenerativ...

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Detalhes bibliográficos
Publicado no:Glia
Main Authors: Zhang, Ping-Wu, Haidet-Phillips, Amanda M., Pham, Jacqueline T., Lee, Youngjin, Huo, Yuqing, Tienari, Pentti J., Maragakis, Nicholas J., Sattler, Rita, Rothstein, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715664/
https://ncbi.nlm.nih.gov/pubmed/26295203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22903
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