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Identifying the Minimal Enzymes Required for Biosynthesis of Epoxyketone Proteasome Inhibitors
Epoxyketone proteasome inhibitors have attracted much interest due to their potential as anti-cancer drugs. While the biosynthetic gene clusters for several peptidyl epoxyketone natural products have recently been identified, the enzymatic logic involved in the formation of the terminal epoxyketone...
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| Udgivet i: | Chembiochem |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4715529/ https://ncbi.nlm.nih.gov/pubmed/26477320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500496 |
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