Leucine‐rich repeat kinase 2 interacts with p21‐activated kinase 6 to control neurite complexity in mammalian brain

Leucine‐rich repeat kinase 2 (LRRK2) is a causative gene for Parkinson's disease, but the physiological function and the mechanism(s) by which the cellular activity of LRRK2 is regulated are poorly understood. Here, we identified p21‐activated kinase 6 (PAK6) as a novel interactor of the GTPase...

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Detalhes bibliográficos
Publicado no:J Neurochem
Main Authors: Civiero, Laura, Cirnaru, Maria Daniela, Beilina, Alexandra, Rodella, Umberto, Russo, Isabella, Belluzzi, Elisa, Lobbestael, Evy, Reyniers, Lauran, Hondhamuni, Geshanthi, Lewis, Patrick A., Van den Haute, Chris, Baekelandt, Veerle, Bandopadhyay, Rina, Bubacco, Luigi, Piccoli, Giovanni, Cookson, Mark R., Taymans, Jean‐Marc, Greggio, Elisa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
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ORIGINAL ARTICLES
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715492/
https://ncbi.nlm.nih.gov/pubmed/26375402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13369
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