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Pathogenic LRRK2 requires secondary factors to induce cellular toxicity
Pathogenic mutations in the leucine-rich repeat kinase 2 (LRRK2) gene belong to the most common genetic causes of inherited Parkinson’s disease (PD) and variations in its locus increase the risk to develop sporadic PD. Extensive research efforts aimed at understanding how changes in the LRRK2 functi...
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| Publicat a: | Biosci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Portland Press Ltd.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7560525/ https://ncbi.nlm.nih.gov/pubmed/32975566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20202225 |
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