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Multiple-Hit Hypothesis in Parkinson’s Disease: LRRK2 and Inflammation

The multiple hit hypothesis for Parkinson’s disease (PD) suggests that an interaction between multiple (genetic and/or environmental) risk factors is needed to trigger the pathology. Leucine-Rich Repeat Kinase 2 (LRRK2) is an interesting protein to study in this context and is the focus of this revi...

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Detaylı Bibliyografya
Yayımlandı:Front Neurosci
Asıl Yazarlar: Cabezudo, Diego, Baekelandt, Veerle, Lobbestael, Evy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7199384/
https://ncbi.nlm.nih.gov/pubmed/32410948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.00376
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