Discovery of Influenza A Virus Sequence Pairs and Their Combinations for Simultaneous Heterosubtypic Targeting that Hedge against Antiviral Resistance

The multiple circulating human influenza A virus subtypes coupled with the perpetual genomic mutations and segment reassortment events challenge the development of effective therapeutics. The capacity to drug most RNAs motivates the investigation on viral RNA targets. 123,060 segment sequences from...

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Detaylı Bibliyografya
Yayımlandı:PLoS Comput Biol
Asıl Yazarlar: Wee, Keng Boon, Lee, Raphael Tze Chuen, Lin, Jing, Pramono, Zacharias Aloysius Dwi, Maurer-Stroh, Sebastian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2016
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714944/
https://ncbi.nlm.nih.gov/pubmed/26771381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004663
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