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Discovery of Influenza A Virus Sequence Pairs and Their Combinations for Simultaneous Heterosubtypic Targeting that Hedge against Antiviral Resistance

The multiple circulating human influenza A virus subtypes coupled with the perpetual genomic mutations and segment reassortment events challenge the development of effective therapeutics. The capacity to drug most RNAs motivates the investigation on viral RNA targets. 123,060 segment sequences from...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Wee, Keng Boon, Lee, Raphael Tze Chuen, Lin, Jing, Pramono, Zacharias Aloysius Dwi, Maurer-Stroh, Sebastian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714944/
https://ncbi.nlm.nih.gov/pubmed/26771381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004663
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