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Discovery of Influenza A Virus Sequence Pairs and Their Combinations for Simultaneous Heterosubtypic Targeting that Hedge against Antiviral Resistance

The multiple circulating human influenza A virus subtypes coupled with the perpetual genomic mutations and segment reassortment events challenge the development of effective therapeutics. The capacity to drug most RNAs motivates the investigation on viral RNA targets. 123,060 segment sequences from...

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Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Wee, Keng Boon, Lee, Raphael Tze Chuen, Lin, Jing, Pramono, Zacharias Aloysius Dwi, Maurer-Stroh, Sebastian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714944/
https://ncbi.nlm.nih.gov/pubmed/26771381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004663
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