Efficacy of Rifampin Plus Clofazimine in a Murine Model of Mycobacterium ulcerans Disease

Treatment of Buruli ulcer, or Mycobacterium ulcerans disease, has shifted from surgical excision and skin grafting to antibiotic therapy usually with 8 weeks of daily rifampin (RIF) and streptomycin (STR). Although the results have been highly favorable, administration of STR requires intramuscular...

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Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: Converse, Paul J., Tyagi, Sandeep, Xing, Yalan, Li, Si-Yang, Kishi, Yoshito, Adamson, John, Nuermberger, Eric L., Grosset, Jacques H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714850/
https://ncbi.nlm.nih.gov/pubmed/26042792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003823
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