Activities of Rifampin, Rifapentine and Clarithromycin Alone and in Combination against Mycobacterium ulcerans Disease in Mice

BACKGROUND: Treatment of Mycobacterium ulcerans disease, or Buruli ulcer (BU), has shifted from surgery to treatment with streptomycin(STR)+rifampin(RIF) since 2004 based on studies in a mouse model and clinical trials. We tested two entirely oral regimens for BU treatment, rifampin(RIF)+clarithromy...

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Bibliographic Details
Main Authors: Almeida, Deepak, Converse, Paul J., Ahmad, Zahoor, Dooley, Kelly E., Nuermberger, Eric L., Grosset, Jacques H.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014976/
https://ncbi.nlm.nih.gov/pubmed/21245920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000933
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