Accelerated Detection of Mycolactone Production and Response to Antibiotic Treatment in a Mouse Model of Mycobacterium ulcerans Disease

Diagnosis of the neglected tropical disease, Buruli ulcer, can be made by acid-fast smear microscopy, specimen culture on mycobacterial growth media, polymerase chain reaction (PCR), and/or histopathology. All have drawbacks, including non-specificity and requirements for prolonged culture at 32°C,...

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Detalhes bibliográficos
Main Authors: Converse, Paul J., Xing, Yalan, Kim, Ki Hyun, Tyagi, Sandeep, Li, Si-Yang, Almeida, Deepak V., Nuermberger, Eric L., Grosset, Jacques H., Kishi, Yoshito
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3879254/
https://ncbi.nlm.nih.gov/pubmed/24392174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002618
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