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Norepinephrine protects against Aβ toxicity via TrkB

The locus coeruleus (LC), the brainstem noradrenergic nucleus that is the sole source of norepinephrine (NE) in the forebrain, is one of the first structures affected in Alzheimer’s disease. Experimental ablation of the LC exacerbates, while increasing NE abates, AD-like neuropathology and cognitive...

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Foilsithe in:J Alzheimers Dis
Main Authors: Liu, Xia, Ye, Keqiang, Weinshenker, David
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714587/
https://ncbi.nlm.nih.gov/pubmed/25208620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-141062
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