Protection of Spiral Ganglion Neurons from Degeneration Using Small-Molecule TrkB Receptor Agonists

Neurotrophins (NTs) play essential roles in the development and survival of neurons in PNS and CNS. In the cochlea, NTs [e.g., NT-3, brain-derived neurotrophic factor (BDNF)] are required for the survival of spiral ganglion neurons (SGNs). Preservation of SGNs in the cochlea of patients suffering se...

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Main Authors: Yu, Qing, Chang, Qing, Liu, Xia, Wang, Yunfeng, Li, Huawei, Gong, Shusheng, Ye, Keqiang, Lin, Xi
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3735884/
https://ncbi.nlm.nih.gov/pubmed/23926258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0854-13.2013
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