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Small molecule BDNF mimetics activate TrkB signaling and prevent neuronal degeneration in rodents
Brain-derived neurotrophic factor (BDNF) activates the receptor tropomyosin-related kinase B (TrkB) with high potency and specificity, promoting neuronal survival, differentiation, and synaptic function. Correlations between altered BDNF expression and/or function and mechanism(s) underlying numerou...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2860903/ https://ncbi.nlm.nih.gov/pubmed/20407211 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI41356 |
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