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Small-molecule trkB agonists promote axon regeneration in cut peripheral nerves

Treatments with two-small molecule tropomyosin receptor kinase B (trkB) ligands, 7,8 dihydroxyflavone (7,8 DHF) and deoxygedunin, were evaluated for their ability to promote the regeneration of cut axons in injured peripheral nerves in mice in which sensory and motor axons are marked by YFP. Periphe...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: English, Arthur W., Liu, Kevin, Nicolini, Jennifer M., Mulligan, Amanda M., Ye, Keqiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791704/
https://ncbi.nlm.nih.gov/pubmed/24043773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303646110
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