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Small-molecule trkB agonists promote axon regeneration in cut peripheral nerves

Treatments with two-small molecule tropomyosin receptor kinase B (trkB) ligands, 7,8 dihydroxyflavone (7,8 DHF) and deoxygedunin, were evaluated for their ability to promote the regeneration of cut axons in injured peripheral nerves in mice in which sensory and motor axons are marked by YFP. Periphe...

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Detalhes bibliográficos
Main Authors: English, Arthur W., Liu, Kevin, Nicolini, Jennifer M., Mulligan, Amanda M., Ye, Keqiang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3791704/
https://ncbi.nlm.nih.gov/pubmed/24043773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303646110
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