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Norepinephrine protects against Aβ toxicity via TrkB
The locus coeruleus (LC), the brainstem noradrenergic nucleus that is the sole source of norepinephrine (NE) in the forebrain, is one of the first structures affected in Alzheimer’s disease. Experimental ablation of the LC exacerbates, while increasing NE abates, AD-like neuropathology and cognitive...
Gardado en:
| Publicado en: | J Alzheimers Dis |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714587/ https://ncbi.nlm.nih.gov/pubmed/25208620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-141062 |
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