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Binding Affinities among DNA Helicase-Primase, DNA Polymerase, and Replication Intermediates in the Replisome of Bacteriophage T7

The formation of a replication loop on the lagging strand facilitates coordinated synthesis of the leading- and lagging-DNA strands and provides a mechanism for recycling of the lagging-strand DNA polymerase. As an Okazaki fragment is completed, the loop is released, and a new loop is formed as the...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Zhang, Huidong, Tang, Yong, Lee, Seung-Joo, Wei, Zeliang, Cao, Jia, Richardson, Charles C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714229/
https://ncbi.nlm.nih.gov/pubmed/26620561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.698233
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