Regulation of polycystin-1 ciliary trafficking by motifs at its C-terminus and polycystin-2 but not by cleavage at the GPS site

Failure to localize membrane proteins to the primary cilium causes a group of diseases collectively named ciliopathies. Polycystin-1 (PC1, also known as PKD1) is a large ciliary membrane protein defective in autosomal dominant polycystic kidney disease (ADPKD). Here, we developed a large set of PC1...

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Detaylı Bibliyografya
Yayımlandı:J Cell Sci
Asıl Yazarlar: Su, Xuefeng, Wu, Maoqing, Yao, Gang, El-Jouni, Wassim, Luo, Chong, Tabari, Azadeh, Zhou, Jing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712779/
https://ncbi.nlm.nih.gov/pubmed/26430213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.160556
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