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Retromer associates with the cytoplasmic amino-terminus of polycystin-2

Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic human disease, with around 12.5 million people affected worldwide. ADPKD results from mutations in either PKD1 or PKD2, which encode the atypical G-protein coupled receptor polycystin-1 (PC1) and the transient receptor...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Tilley, Frances C., Gallon, Matthew, Luo, Chong, Danson, Chris M., Zhou, Jing, Cullen, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6031323/
https://ncbi.nlm.nih.gov/pubmed/29724910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.211342
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