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Atypical parkinsonism–associated retromer mutant alters endosomal sorting of specific cargo proteins
The retromer complex acts as a scaffold for endosomal protein complexes that sort integral membrane proteins to various cellular destinations. The retromer complex is a heterotrimer of VPS29, VPS35, and VPS26. Two of these paralogues, VPS26A and VPS26B, are expressed in humans. Retromer dysfunction...
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| Yayımlandı: | J Cell Biol |
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| Asıl Yazarlar: | , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4987296/ https://ncbi.nlm.nih.gov/pubmed/27528657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201604057 |
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