Mammalian Retromer Is an Adaptable Scaffold for Cargo Sorting from Endosomes

Metazoan retromer (VPS26/VPS35/VPS29) associates with sorting nexins on endosomal tubules to sort proteins to the trans-Golgi network or plasma membrane. Mechanisms of metazoan retromer assembly remain undefined. We combine single-particle cryoelectron microscopy with biophysical methods to uncover...

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Bibliografiska uppgifter
I publikationen:Structure
Huvudupphovsmän: Kendall, Amy K., Xie, Boyang, Xu, Peng, Wang, Jue, Burcham, Rodger, Frazier, Meredith N., Binshtein, Elad, Wei, Hui, Graham, Todd R., Nakagawa, Terunaga, Jackson, Lauren P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2020
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7145723/
https://ncbi.nlm.nih.gov/pubmed/32027819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.01.009
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