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Mammalian Retromer Is an Adaptable Scaffold for Cargo Sorting from Endosomes
Metazoan retromer (VPS26/VPS35/VPS29) associates with sorting nexins on endosomal tubules to sort proteins to the trans-Golgi network or plasma membrane. Mechanisms of metazoan retromer assembly remain undefined. We combine single-particle cryoelectron microscopy with biophysical methods to uncover...
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| 出版年: | Structure |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7145723/ https://ncbi.nlm.nih.gov/pubmed/32027819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.01.009 |
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