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Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting
Human retromer, a heterotrimer of VPS26 (VPS26A or VPS26B), VPS35 and VPS29, orchestrates the endosomal retrieval of internalised cargo and promotes their cell surface recycling, a prototypical cargo being the glucose transporter GLUT1 (also known as SLC2A1). The role of retromer in the retrograde s...
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| Gepubliceerd in: | J Cell Sci |
|---|---|
| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Company of Biologists Ltd
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7420817/ https://ncbi.nlm.nih.gov/pubmed/32747499 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.246033 |
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