Germline quality control: eEF2K stands guard to eliminate defective oocytes

The control of germline quality is critical to reproductive success and survival of a species; however, the mechanisms underlying this process remain unknown. Here we demonstrate that elongation factor 2 kinase (eEF2K), an evolutionarily conserved regulator of protein synthesis, functions to maintai...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Chu, Hsueh-Ping, Liao, Yi, Novak, James S., Hu, Zhixian, Merkin, Jason J., Shymkiv, Yuriy, Braeckman, Bart P., Dorovkov, Maxim V., Nguyen, Alexandra, Clifford, Peter M., Nagele, Robert G., Harrison, David E., Ellis, Ronald E., Ryazanov, Alexey G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712648/
https://ncbi.nlm.nih.gov/pubmed/24582807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.01.027
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