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Germline quality control: eEF2K stands guard to eliminate defective oocytes

The control of germline quality is critical to reproductive success and survival of a species; however, the mechanisms underlying this process remain unknown. Here we demonstrate that elongation factor 2 kinase (eEF2K), an evolutionarily conserved regulator of protein synthesis, functions to maintai...

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Bibliografske podrobnosti
izdano v:Dev Cell
Main Authors: Chu, Hsueh-Ping, Liao, Yi, Novak, James S., Hu, Zhixian, Merkin, Jason J., Shymkiv, Yuriy, Braeckman, Bart P., Dorovkov, Maxim V., Nguyen, Alexandra, Clifford, Peter M., Nagele, Robert G., Harrison, David E., Ellis, Ronald E., Ryazanov, Alexey G.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712648/
https://ncbi.nlm.nih.gov/pubmed/24582807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2014.01.027
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