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Pharmacological eEF2K activation promotes cell death and inhibits cancer progression

Activation of the elongation factor 2 kinase (eEF2K) leads to the phosphorylation and inhibition of the elongation factor eEF2, reducing mRNA translation rates. Emerging evidence indicates that the regulation of factors involved in protein synthesis may be critical for controlling diverse biological...

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Dettagli Bibliografici
Pubblicato in:EMBO Rep
Autori principali: De Gassart, Aude, Demaria, Olivier, Panes, Rébecca, Zaffalon, Léa, Ryazanov, Alexey G, Gilliet, Michel, Martinon, Fabio
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048377/
https://ncbi.nlm.nih.gov/pubmed/27572820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642194
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