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Pharmacological eEF2K activation promotes cell death and inhibits cancer progression

Activation of the elongation factor 2 kinase (eEF2K) leads to the phosphorylation and inhibition of the elongation factor eEF2, reducing mRNA translation rates. Emerging evidence indicates that the regulation of factors involved in protein synthesis may be critical for controlling diverse biological...

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Dades bibliogràfiques
Publicat a:EMBO Rep
Autors principals: De Gassart, Aude, Demaria, Olivier, Panes, Rébecca, Zaffalon, Léa, Ryazanov, Alexey G, Gilliet, Michel, Martinon, Fabio
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048377/
https://ncbi.nlm.nih.gov/pubmed/27572820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642194
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