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Pharmacological eEF2K activation promotes cell death and inhibits cancer progression

Activation of the elongation factor 2 kinase (eEF2K) leads to the phosphorylation and inhibition of the elongation factor eEF2, reducing mRNA translation rates. Emerging evidence indicates that the regulation of factors involved in protein synthesis may be critical for controlling diverse biological...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: De Gassart, Aude, Demaria, Olivier, Panes, Rébecca, Zaffalon, Léa, Ryazanov, Alexey G, Gilliet, Michel, Martinon, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048377/
https://ncbi.nlm.nih.gov/pubmed/27572820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201642194
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