Increased expression of the PI3K catalytic subunit p110δ underlies elevated S6 phosphorylation and protein synthesis in an individual with autism from a multiplex family

BACKGROUND: Dysfunctions in the PI3K/mTOR pathway have gained a lot of attention in autism research. This was initially based on the discovery of several monogenic autism spectrum disorders with mutations or defects in PI3K/mTOR signaling components. Recent genetic studies corroborate that defective...

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Bibliografiset tiedot
Julkaisussa:Mol Autism
Päätekijät: Poopal, Ashwini C., Schroeder, Lindsay M., Horn, Paul S., Bassell, Gary J., Gross, Christina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712554/
https://ncbi.nlm.nih.gov/pubmed/26770665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13229-015-0066-4
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